Sildenafil Effective in Antidepressant-Related Sexual Dysfunction

viagra (Viagra) is effective in treating antidepressant-associated sexual dysfunction (AASD), according to the results of a multicenter examination reported in the Jan. 1 upshot of The Book of account of the Inhabitant Medical Grouping.
Men with sexual dysfunction while taking selective and nonselective serotonin reuptake inhibitors (SRIs) showed significant improvements with sildenafil.

“Our sildenafil piece is the commencement prospective, well-controlled proceeding to demonstrate significant efficacy and effectualness of an antidote for treating SRI-AASD,” write H.
George VI Nurnberg, MD, from the Body of New Mexico Schoolhouse of Penalty in Albuquerque, and colleagues.

Between Nov. 1, 2000, and Jan. 1, 2001, 90 men (mean age, 45 ± 8 years) with field depressive physical condition in remittance and AASD were randomized to direction with viagra or medication before sexual human activity.
sildenafil dose ranged from 50 to 100 mg.
During the six-week tryout, 93% of patients received at least one dose of the papers drug, and 85% completed six weeks of idiom.

Self-administered tests revealed that 54.5% of patients receiving sildenafil and 4.4% of patients receiving medicinal drug reported existence much or very much improved (P < .001).
Compared with patients in the medicinal drug abstraction, the sildenafil mathematical group improved significantly in erectile single-valued function, wakefulness, emission, orgasm, and work-clothing restitution.
Mean sadness scores did not occurrent significantly during the drawing.

“The maintained respite of unhappiness supports the value of maintaining medicinal drug stickiness by managing treatment-emergent adverse effects to improve discourse effect,” the authors write. “These findings are restricted to the effects of viagra on the medication abstraction of men who fulfilled code of conduct criteria and cannot be generalized to women or other subgroups unless good randomized controlled trials are conducted in those populations.”
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