Skin Diseases in Women: Dermatoses Not Linked to Pregnancy

Skin Diseases in Women: Dermatoses Not Linked to Pregnancy

Acne Vulgaris

Form of disease. Acne vulgaris is one of the most common inflammatory disorders for which women seek management.
Acne lesions develop from a assemblage of increased androgen (which causes increased sebaceous gland capability and follicular keratinization) and the work of Propionibacterium acnes.
Lipases of these bacteria causal agent the partitioning of sebum into free fatty acids, which in turn suit acute excitation.

The earmark of acne vulgaris is the attendance of comedones (white, and blackheads) on the face.
Inflamed papules and pustules are features of more severe acne vulgaris (Fig. 4).
In severe acne, nodules and cysts appear (Fig. 5) and may causal agent severe scarring later.
Besides the face, the external body part and back may also be affected.

Percept 4. (click simulacrum to zoom) Inflamed papules and pustules, features of severe acne vulgaris.

Soma 5. (click person to zoom) Nodular and cystic lesions may appear in extremity cases of acne, causing severe scarring.

Aggravating factors in acne vulgaris include heat, cosmetics, premenstrual hormone changes, and some medicaments.

First derivative diagnoses. The computation diagnoses of acne vulgaris include rosacea (presence of telangiectasia, erythema, and flushing), occurrent dermatitis (usually pruritic and scaly), and disease of the skin erythematosus (often photosensitive with epidermal weakening and follicular plugging).

Tending. Women often seek direction to improve their boilersuit appearing, as well as to prevent permanent scarring.
The attention of mild acne vulgaris consists of the use of keratolytic, bacteriostatic, and antiinflammatory agents–for instance, benzoyl hydrogen peroxide (Clearasil, Clean & Country, Fostex), erythromycin or clindamycin (Cleocin), and tretinoin.

For moderate acne vulgaris, an oral antibiotic is indicated.
Tetracycline is the antibiotic direction of option.
Oral tetracycline 500mg bid, or doxycycline (Vibramycin) 100mg bid, or minocycline (Minocin) 100mg daily may be used. Side effects include cutaneous outbreak, gastrointestinal perturbation, vaginal candidiasis, and photosensitivity (particularly with doxycycline and minocycline).
Alternative antibiotics include erythromycin 500mg bid.
Antibiotics are administered for prolonged periods, ranging from 3 months to 1 or more period of time.

For women who are taking an oral contraceptive (OC), a cyproterone-acetate (antiandrogen)-containing OC may be used.
The antiprogesterone effects of contraceptives containing high estrogens have also been used in women with perimenstrual acne flares.
In women who are already taking an OC, switching to a high-estrogen OC can help.
Cyproterone-containing contraceptives are sometimes more effective than those without cyproterone, but these contraceptives are not readily available in every nation.

The action between oral antibiotics (in part tetracycline and erythromycin) and OC is a worry to most physicians.
Conflicting reports have indicated that concomitant presidency of tetracycline and erythromycin may interfere with the contraceptive capability of OCs.
There are no proper status studies to documentation this; however, most physicians advise their patients to use other contraceptive methods when taking tetracycline and erythromycin over the long-term.

For severe nodular-cystic acne vulgaris, oral isotretinoin (Accutane) may be indicated. However, isotretinoin is teratogenic and should be avoided in women of childbearing age unless strict contraceptive measures are undertaken.
The drug may also effort other side effects, including skin and mucosal temperance, erythema, cheilitis, epistaxis, and alopecia.
Because the drug may induce hepatitis and hyperlipidemia, patients on isotretinoin should undergo periodic someone part examination and fasting humour lipid monitoring.
A rise in somebody enzymes or in lipids indicates the need to discontinue the drug.

Many women seek artistic style for scarring from untreated acne vulgaris.
Chemical peels with medium-depth peeling agents (Jessner’s mixture and trichloroacetic acid) can improve the pretence of mild acne scars.
This is a part of article Skin Diseases in Women: Dermatoses Not Linked to Pregnancy Taken from "Acne Isotretinoin Accutane" Information Blog